An increasing body of literature suggests that concentrating proteins and exosomes in addition to platelets will improve PRP results, perhaps DRAMATICALLY.
There are over 1,000 different exosomes and proteins found in plasma that cannot be concentrated by a simple tabletop, low G-force, centrifugation process.
Capturing the solid portion of blood plasma is likely to have significant therapeutic value.
Blood plasma contains 91% to 92% water and 8% to 9% solids.
The solid portion of plasma contains extracellular vesicles and proteins; fibrinogen, albumin, globulin, immunoglobulins, and electrolytes.

“This study demonstrates that fibrinogen is safe and a widely available extracellular matrix that can be used as a versatile scaffold for cells.”
(Tatsufumi Mori, et al Fibrinogen supports self-renewal of mesenchymal stem cells under serum-reduced condition through autophagy activation, Biochemical and Biophysical Research Communications, Volume 651, 2023, Pages 70-78)
“In our opinion, fibrin-based matrices have emerged as a promising biological and multipurpose platform due to their high cellular-adhesion capacity."
(Everts, P.A.; et al. Profound Properties of Protein-Rich, Platelet-Rich Plasma Matrices as Novel, Multi-Purpose Biological Platforms in Tissue Repair, Regeneration, and Wound Healing. Int. J. Mol. Sci. 2024, 25, 7914.)

Significant Untapped Potential in Regenerative Medicine